Chief Executive Officer and a member of the board of directors of Rekindle Therapeutics and NextPoint Therapeutics. The business combination is expected to close by the end of the first quarter in 2021, and the company will be Currently, he is President and CEO of two early-stage biotech companies, Rekindle Therapeutics and NextPoint Therapeutics. Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T . iTeos Therapeutics, Inc. (Exact name of registrant as specified in its charter) (Name of Person(s) Filing Proxy Statement, if other than the Registrant) . . NextPoint Financial Inc. (TSX: NPF.U) (TSX: NPF.WT.U) ("NextPoint") announced today that pursuant to NextPoint's previously announced application, the Ontario Securities Commission (the "OSC"), as . Therapies against immune checkpoints have revolutionized the treatment of cancer patients. Pipeline. 5 NextPoint Therapeutics Inc., Cambridge, MA 02142, USA. We use our genome-wide, CRISPR-enabled SNIPRx platform to systematically discover and develop highly targeted cancer therapies focused on genomic instability . The results show 92% of voted shares were in support of the deal. Scott is an accomplished scientist with significant biotech experience and a strong research and drug development track record who has founded and held several senior Since 2020, Nexbiome Therapeutics has been . . At Intellia, we are building a full-spectrum, product-driven biotechnology company focused on our mission of developing and commercializing potentially curative genome editing. Learn More about Ansbert Gadicke's net worth. Sterling National Bank is providing $2.5 million in a senior facility, and Bigfoot Capital is providing $2.0m in mezzanine financing. Latest News. Matt is also an Executive Partner at MPM Capital, serves as Chairman of Turmeric Acquisition Corporation, and is on the Boards of Directors of iTeos Therapeutics and NextPoint Therapeutics. INVESTMENT PORTFOLIO (unaudited)(continued) As of June 30, 2021 NexPointStrategicOpportunitiesFund Shares Value ($) Rights-0.2% UTILITIES - 0.2% 1,624,994 Matt also serves as Chairman of Turmeric Acquisition Corporation (NASDAQ: TMPM), and on the Boards of Directors of iTeos Therapeutics (NASDAQ: ITOS) and NextPoint Therapeutics, all MPM portfolio companies. HURST, Texas, May 06, 2022 (GLOBE NEWSWIRE) -- NextPoint Financial Inc. (TSX: NPF.U, NPF.WT.U and OTC Pink: NACQF) ("NextPoint") today announced that Scott Wright has been named Chief . Currently, he is President and CEO of two early-stage biotech companies, Rekindle Therapeutics and NextPoint Therapeutics. 3.3 star. Reporting to the Chief Scientific Officer, the Vice President Clinical Development will be responsible for . May 2, 2022 The team aims to leverage the project's results to launch a phase 1 clinical trial in RCC patients to study the safety and efficacy of the developed antibodies and are partnered with NextPoint Therapeutics to work on pharmaceutical development for their antibody cancer therapy. Eureka Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing transformative technology platforms that can access cancer-specific targets and harness the evolutionary power of T cells for the treatment of solid tumors and other malignancies. The base salary for Senior Scientist ranges from $143,176 to $175,626 with the average base salary of $158,934. Let's Talk! Browse jobs with BioSpace Featured Employers here . NextPoint Learning is an online, on-demand learning platform for skilled trades. The estimated net worth of Ansbert Gadicke is at least $4.54 million as of September 13th, 2021. NextPoint Therapeutics is an exciting early-stage Boston-area startup company working tier of immuno-oncology. The total cash compensation, which includes base, and annual incentives, can . YourBioHealth (formerly Seventh Sense Biosystems) Zilker Ultimate Topco, Inc. (d/b/a ESO) (Emergency Reporting) Zingdom / Convoq. May 10, 2022 a Revance Reports First Quarter 2022 Financial Results, Provides Corporate Update. Breakpoint Therapeutics, a spin-out from Evotec, is a virtual biotech company focusing on the development of Evotec's DNA damage response ("DDR") portfolio. 6 Departments of Neurology and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Detlev Biniszkiewicz, Ph.D. - MPM Capital Dr. Detlev Biniszkiewicz is President and CEO of two early-stage MPM portfolio companies, Rekindle Therapeutics and NextPoint Therapeutics. NEXTPOINT THERAPEUTICS, INC. DELAWARE CORPORATION: WRITE REVIEW: Address: Corporation Trust Center 1209 Orange St Wilmington, DE 19801: Registered Agent: The Corporation Trust Company: Filing Date: September 17, 2018: File Number: 7059407: Contact Us About The Company Profile For Nextpoint Therapeutics, Inc. xingxing.zang@einsteinmed.org. Dr. Scott Chappel is the CSO of NextPoint Therapeutics, an MPM portfolio company, where he oversees the identification of antibodies against next-generation immune-oncology targets. Every day, more than 500 researchers and staff come to work at Intellia. By systematically screening human tumor cells, the Company has identified a number of novel targets and is building a pipeline of drug candidates against them. These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Senior Scientist in Boston, MA. FACT SHEET Q1 2021 Symbol Class A: HMEAX Class C: HMECX Class Z: HMEZX2 Inception Date (Class Z) January 20, 2015 Fund Manager Jim Dondero, CFA, Co-Founder Eric Fritz, Portfolio Manager Brad Heiss, CFA, Portfolio Manager Merger Arb Deals 53 We're committed to the mission of advancing breakthrough science to deliver therapies that patients and eye care professionals need. Our science. OS Fund invests in entrepreneurs commercializing breakthrough discoveries in genomics, synthetic biology, computationally derived therapeutics, advanced materials, and diagnostics. Matthew Roden, PhD Director Matthew Roden is President and Chief Executive Officer at Aktis Oncology, and a member of the Aktis Board of Directors. intellectual property has been licensed to NextPoint Therapeutics, which is developing a pipeline of therapeutic antibody candidates targeting KIR3DL3 and HHLA2. Public asset : 3,778,634 USD. Our mission is to enable improved clinical regimes through cre . Our team of drug development veterans work closely with trusted clinical and research partners to advance candidates in both a timely and capital-efficient way. innovation. Associate Director, NextPoint Therapeutics, Boston, Massachusetts; Health Data Science Leader, Insight Data Science, San Francisco, California; Self-employed, Medical Writer and Editor at CRL MedWrite; Senior Regulatory Specialist at Enable Injections, Inc., Cincinnati, Ohio; Pharmacogenomics Project Manager, Vanderbilt University Medical Center Adimab, LLC, the global leader in the discovery and optimization of fully human monoclonal and bispecific antibodies, today announced that in 2021 it entered into agreements with 13 new companies. These are targeted therapies that safely harness the superior anticancer potency of alpha-emitting . Kiddy - Reward Kids For Good Behavior - Parenting. Prior to joining Strand Therapeutics, Sarah was a . Founded by MPM Capital, NextPoint Therapeutics has assembled a team of proven drug developers to build a broad strategic pipeline of first-in-class immunotherapies based on this validated checkpoint axis, with the goal of delivering new options to people with cancer. iOmx Therapeutics focuses on the development of next-generation, first-in-class cancer immune-checkpoint inhibitors. Delivering targeted alpha-emitting drugs with precision pharmacology. TCR 2 researcher at the lab bench. SkillMill. In addition, Adimab announced the expansion of 14 of its current partnerships and the achievement of 52 technical and development milestones across numerous collaborations. Branch of NEXTPOINT THERAPEUTICS, INC. (Delaware (US)) Registered Address 450 KENDALL ST. CAMBRIDGE 02142 MA USA Agent Name REGISTERED AGENT SOLUTIONS, INC Agent Address 44 SCHOOL STREET, SUITE 505, BOSTON, MA, 02108 Directors / Officers ANSBER GADICKE, director DETLEV BINISZKIEWICZ, director DETLEV BINISZKIEWICZ, president MATTHEW RODEN, director TCR Therapeutics. The Company was founded on the successful concept of cancer immune . Faber Daeufer & Itrato is a boutique law firm providing corporate and transactional counsel in the drug, life sciences, and emerging technology industries. Jean Birch joined the board on, and has served as NextPoint's Lead Director since, July 2, 2021, when the Company's completed its qualifying acquisition. is a cofounder of NextPoint Therapeutics Inc. Dr. Detlev Biniszkiewicz is a serial entrepreneur and an experienced biopharma executive who brings deep knowledge of oncology and immuno-oncology to his role at MPM. September 1, 2021. Sarah is a Scientist leading Vector Engineering efforts at Strand Therapeutics. Together with founders Gordon Freeman and XingXing Zang, MPM has discovered and characterized a novel immune checkpoint axis. Get new jobs for NextPoint Therapeutics by email Follow NextPoint Therapeutics Since July 2020, Ms. Birch has served . More by Interplay Learning. Butterfly Network and Longview Acquisition announced today that they have entered into a definitive merger agreement. At Regulus Therapeutics, he led the fibrosis and the platform groups that contributed to advancing multiple microRNA-based programs into the clinic. We are currently looking to add a Vice President Clinical Development to our fast moving, roll-up your sleeves team environment. He also serves as chairman of the board of directors of two private companies, NextPoint Therapeutics and Orna Therapeutics and as a member of the board of directors of ElevateBio, also a private company. At iTeos, we are specializing in targeted immunotherapies for people living with cancer. Founded and. NextPoint Therapeutics is an exciting early stage Boston-area startup company working at the frontier of immune-oncology. 1 minute read. Driven by an interest in how parts work together, whether in a biological system or a research team, Sarah works with other members of the Molecular Biology department to develop Strand's mRNA vector toolkit. We are a biopharmaceutical company focused on the discovery, development, and commercialization of first-in-class therapies to treat ophthalmic disease. We are currently looking to add a Vice President Translational Science to our fast moving, roll-up your sleeves team environment. Mira Therapeutics. Aktis Oncology is a biotechnology company pioneering the discovery and development of a new class of targeted radiopharmaceuticals to treat a broad range of solid tumor cancers. 4043 N Ravenswood Ave, #317, Chicago, 60613. hello@nextpoint.com. This approach is designed to complement natural tumor recognition, direct V9V2 T cells to the . Detlev is a serial entrepreneur and an experienced biopharma executive who brings deep knowledge of oncology and immuno-oncology to his role at MPM. Repare Therapeutics is a leading clinical-stage precision oncology company enabled by our proprietary synthetic lethality approach to discovering and developing novel therapeutics. We are currently looking to add a Vice President Translational. Miami. With deep expertise in chemistry and structure-based drug discovery, Nuvalent is creating precisely targeted therapies for patients with cancer. Prior to his tenure at BlueRock Therapeutics, Inc., Mr. Trigilio was a Director, Healthcare Investment Banking at RBC Capital Markets LLC . to transform cancer therapy. iTeos Therapeutics is pioneering the discovery and development of highly differentiated immuno-oncology therapeutics for patients. Dr. Matthew Roden is the President and CEO and serves on the board of Aktis Oncology, an MPM portfolio company. In 1975, Lcr35 became the active ingredient of the first microbiome-derived medicinal product in the world: Antibiophilus. Nextpoint Therapeutics, Inc. in Cambridge, MA | Company Info & Reviews Company Information Company Contacts ANSBER GADICKE Director 450 Kendall St. Cambridge, MA 02142 DETLEV BINISZKIEWICZ Director 450 Kendall St. Cambridge, MA 02142 DETLEV BINISZKIEWICZ President 450 Kendall St. Cambridge, MA 02142 STEPHEN CURTIS Director 450 Kendall St. X Also called gene editing. NEXTPOINT THERAPEUTICS, INC. Company Number 7059407 Incorporation Date 17 September 2018 (over 3 years ago) Company Type Corporation Jurisdiction Delaware (US) Agent Name THE CORPORATION TRUST COMPANY Agent Address CORPORATION TRUST CENTER 1209 ORANGE ST, WILMINGTON, New Castle, DE, 19801 Directors / Officers THE CORPORATION TRUST COMPANY, agent NextPoint is developing medications targeting this novel axis to expand the benefit of immunotherapies to more cancer patients. Reporting to the Chief Scientific Officer, the Vice President will build our Translational Medicine . Genome editing collectively refers to a set of technologies, including CRISPR/Cas9, that can be used to cut and modify DNA. To systemically evaluate cell-intrinsic regulators of antitumor immunity, we developed an in vitro and in vivo CRISPR screening using the murine KP lung cancer model (Fig. He holds the position of Managing Director at MPM Capital Inc . Nexbiome Therapeutics was built on this heritage, made of innovation and audacity, and validated R&D assets. Our Commitment. Dr. Zang is professor of microbiology & immunology, of medicine, of urology, the Louis Goldstein Swan Chair in Cancer Research at Einstein, and a member of the This net worth estimate does not reflect any other investments that Dr. Gadicke may own. Our novel Gammabody platform generates bispecific gamma delta T cell engager therapeutics that activate a unique and relatively abundant effector gamma delta T cell subset called V9V2 (Vgamma9 Vdelta2) T cells. Fully engaging the T-cell receptor to transform the treatment of solid tumors. Most marketed immunotherapies inhibit two proteins in particular: PD-L1 on tumor cells and PD-1 on T cells. (888) 929-NEXT. 18851 NE 29th Ave. 2nd Floor. Eli5ed : Explain-ed like I am 5. Xtuit Pharmaceuticals. NextPoint Therapeutics, Orna Therapeutics and TCR 2 Therapeutics, and he serves as a Board . scientific founders. Adimab has also partnered with many early-stage venture-backed companies, including Amagma, Cygnal, Dragonfly, iOmx, NextPoint, Pliant, Tizona, TRex Bio and others, as well as mid-size public . One of the candidates, lademirsen, is in a phase 2 trial for the treatment of Alport Syndrome. NEW YORK& SAN DIEGO---- Bristol Myers Squibb and . Learn about our pipeline. The company serves the Canadian medical and adult-use markets with its brand portfolio that includes: 48North, an innovative and high-quality cannabis brand focused on thoughtfully crafted . Prior to joining MPM, Detlev was the President and CEO . Questions about Nextpoint? world-class team. Director of iTeos Therapeutics. 1A).KP cells were engineered to express Cas9, and two clonal KP-Cas9 cell lines (clones 7 and 9) were selected to provide . 7 Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. In vitro and in vivo screening identified Tsc1/Tsc2 as candidates of immune modulators in NSCLC. We are currently seeking a highly motivated Project Manager to join our. Aventura, FL 33180 (786) 591-7001 NextPoint Therapeutics is an exciting early stage Boston-area startup company working at the frontier of immune-oncology. There was no mention of any redemptions, although the SPAC has consistently traded well above $11 since the deal was announced in March and . Website - Coming Soon PREV NEXT We seek to partner with future literate entrepreneurs who understand our unique time and place in history, and who possess the ambition to author a better future for . We'd love to hear from you. NextPoint Therapeutics is an exciting early-stage Boston-area startup company working tier of immuno-oncology. Iksuda is an emerging biotechnology company focused on developing antibody-based therapies for the treatment of cancer as well as broader based therapeutics. Genome editing collectively refers to a set of technologies, including CRISPR/Cas9, that can be used to cut and modify DNA. The other authors declare that they have no competing interests. Aktis Oncology is committed to transforming cancer care with novel platform technologies that will enable us to design and develop powerful precision radiopharmaceuticals. Adimab has also partnered with many early-stage venture-backed companies, including Amagma, Cygnal, Dragonfly, iOmx, NextPoint, Pliant, Tizona, TRex Bio and others, as well as mid-size public biopharmaceutical companies such as Acceleron, Alector, Cullinan Oncology, Innovent, Jounce, Mersana, Scholar Rock, Surface Oncology, and others. arrow_forward. Bristol Myers Squibb to Commence All-Cash Tender Offer to Acquire All Outstanding Shares of Turning Point Therapeutics for $76.00 per Share. Pipeline. Outlook Therapeutics is a late clinical-stage biopharmaceutical company working to develop and launch the first FDA-approved ophthalmic formulation of bevacizumab for use in retinal indications, including wet age-related macular degeneration (wet AMD), diabetic macular edema (DME) and branch retinal vein occlusion (BRVO). Prior to that, Dr. Biniszkiewicz served as President and Chief Executive . Summary NextPoint Therapeutics is an exciting early-stage Boston-area startup company working at the frontier of immuno-oncology. Founded by MPM Capital, NextPoint Therapeutics has assembled a team of proven drug developers to build a broad strategic pipeline of first-in-class immunotherapies based on this validated checkpoint axis, with the goal of delivering new options to people with cancer. Inspired to Innovate for Patients With Ophthalmic Disease. Therapeutics pipeline. OncolowPipeline Every trial, result and timeline that matters Stay on top of all the and developments in your area of interest Know all the launch tit4e Competing interests: Y.W., X.R., S.M., and X.Z. CHICAGO, IL, OCTOBER 27, 2021 Nextpoint, the industry-leader in cloud-based eDiscovery and Litigation support software, has secured $4.5 million in non-dilutive, growth capital. Ansbert K. Gadicke. Dr. Gadicke owns 248,170 shares of iTeos Therapeutics stock worth more than $4,541,511 as of May 17th. Age : 63. X Also called gene editing. Turning Point Therapeutics (TPTX) - The biopharmaceutical company's shares more than doubled in premarket trading after agreeing to be acquired by Bristol Myers Squibb (BMY) for $76 per share . April 21, 2022 b Revance Receives FDA Acceptance of BLA Resubmission for DaxibotulinumtoxinA for Injection for Glabellar Lines. 4.1 star. Surface Oncology is developing next generation immunotherapies that target the immune-suppressive tumor microenvironment to attack cancer. Through a combination of internal expertise and external relationships, Cullinan manages a portfolio of pre-clinical and clinical studies with quality and precision. Turning Point Therapeutics, Inc. has a twelve month low of $23.77 and a twelve month high of $83.06. We are motivated by our mission to develop potentially curative genome editing. Cancer immunotherapies are monoclonal antibodies that prevent this tumor cell/T/NK cell interactionby binding to the tumor-cell protein or to the T/NK-cell receptor. X4 Pharmaceuticals (Arsanis) Xactly (Centive) Xant (f/k/a InsideSales) Xfund2 (Experiment Fund II) Xpressdocs. The Power Of. Today, Lyocentre historic R&D has become Nexbiome Therapeutics. Ansbert K. Gadicke is an entrepreneur who founded MPM Capital Inc, MPM BioEquities Adviser LLC and Cerimon Pharmaceuticals, Inc. Turning Point Therapeutics (TPTX) - The biopharmaceutical company's shares more than doubled in premarket trading after agreeing to be acquired by Bristol Myers Squibb (BMY) for $76 per share . NextPoint Learning is an online, on-demand learning platform for skilled trades. Dr. Detlev Biniszkiewicz is a serial entrepreneur and an experienced biopharma executive who brings deep knowledge of oncology and immuno-oncology to his role at MPM. We are currently seeking a highly motivated Project Manager to join our team. Engineered T-cell receptor complex. We'd love to talk to you. Driving progress across multiple technologies and solid tumor types. The enterprise value of the merger is $1.5 billion, with the combined company expected to have an estimated $584 million in cash after closing. NextPoint Therapeutics 650 E. Kendall Street Cambridge MA 02142 United States Tel: (617) 319 7755 Currently, there are no jobs for this employer on BioSpace. are inventors on a pending patent (KIR3DL3 is an inhibitory receptor of the immune system and uses thereof); B.E.-G. is an employee and X.Z. Find the latest MetaStat, Inc. (MTST) stock quote, history, news and other vital information to help you with your stock trading and investing. Linked companies : Cullinan Oncology, Inc. - AlloVir, Inc. - TCR2 Therapeutics Inc. Summary. Learn about our science. Ex Vivo Therapies. Breakpoint Therapeutics' mission is to develop first- and best-in-class oncology drugs that interfere with DNA repair and replication stress pathways to facilitate the cure of . . Our main goal is to develop effective therapies to improve patients' lives. CM Life Sciences II in an 8-K filing said its stockholders approved the proposed merger with SomaLogic. The stock has a market capitalization of $3.71 billion, a price-to-earnings ratio of -13.44 and .